Frontiers of Discovery: SLAC’s Mission to Unveil the Mysteries of Matter and the Cosmos

The BaBar Detector at SLAC with physicist Michael Kelsey inside wearing a red hard hat, 2002. 
(Peter Ginter/SLAC National Accelerator Laboratory)

Part one of a multi-part series on the many scientific institutions in California making ground-breaking discoveries across all fields of science. By some estimates, California has the most scientific-focused, cutting-edge institutions of any place on the planet.

The SLAC National Accelerator Laboratory in Menlo Park, California, is a testament to human curiosity and the pursuit of the unknown. Since its inception in 1962, originally as the Stanford Linear Accelerator Center (as it was previously known), it has been on the forefront of scientific discovery in numerous scientific disciplines. It is truly one of the nation’s great scientific institutions, being at the forefront of numerous major discoveries that have deeply impacted – and will impact – the world. 

Six scientists have received four Nobel prizes for their groundbreaking research conducted at SLAC, which led to the discovery of two elementary particles, confirmed that protons consist of quarks, and elucidated the process by which DNA orchestrates the synthesis of proteins in cells.

Stanford’s Roger Kornberg received the 2006 chemistry Nobel for work on RNA transcriptase, shown on screens.  
(Peter Ginter/SLAC National Accelerator Laboratory)

Administered by Stanford University and sponsored by the U.S. Department of Energy, SLAC has grown into a multifaceted research institution that explores a broad program in atomic and solid-state physics, chemistry, biology, and medicine. The lab employs the use of X-rays generated from synchrotron radiation and a free-electron laser, among other tools, to push the boundaries of our understanding in areas ranging from elementary particle physics to cosmology​​.

SLAC’s roots can be traced back to the construction of the 3.2-kilometer Stanford Linear Accelerator in 1966, the world’s longest linear accelerator at the time. This remarkable structure has been pivotal in fundamental research that led to the discovery of the charm quark in 1976, the quark structure inside protons and neutrons in 1990, and the tau lepton in 1995, each discovery earning a Nobel Prize in Physics​​. This pioneering spirit is also embedded in SLAC’s cultural heritage, having provided a meeting space for the Homebrew Computer Club, which significantly contributed to the home computer revolution of the late 1970s and early 1980s​​. For example, Steve Wozniak debuted the prototype Apple-1 at the Homebrew Computer Club in 1976. 

Steve Jobs and Steve Wozniak
Apple 1

SLAC has also played a significant role in the digital age, hosting the first World Wide Web server outside of Europe in December 1991, a milestone that underscores its contribution beyond the realm of physics​​. In the 1990s, the Stanford Linear Collider delved into the properties of the Z boson, further cementing SLAC’s position at the cutting edge of particle physics research​​.

New projects and experiments are undertaken at SLAC all the time, and new discoveries are constantly being made to help us understand the nature of matter, biological processes and the evolution of the universe, as well as to help bring us into a greener future. In November 2023, a team at SLAC along with the Toyota Motor Company made significant advances in fuel cell efficiency.

The Linac Coherent Light Source (LCLS), a free-electron laser facility, has been a highlight of SLAC’s facilities, providing intense X-ray radiation for diverse research areas since 2009. In September 2023, SLAC fired up the world’s most powerful X-ray laser, the LCLS-II, to explore atomic-scale, ultrafast phenomena that are key to a broad range of applications, from quantum materials to clean energy technologies and medicine.

“This achievement marks the culmination of over a decade of work,” said LCLS-II Project Director Greg Hays. “It shows that all the different elements of LCLS-II are working in harmony to produce X-ray laser light in an entirely new mode of operation.”  

It was in the facility that scientists and researchers developed the first X-ray free-electron lasers (XFELs). XFELs are like X-ray microscopes, and generate exceptionally bright and fleeting bursts of X-ray light, enabling researchers to observe the dynamics of molecules, atoms, and electrons with unparalleled clarity, exactly as these events unfold in their native, rapid timescales—a realm where the intricacies of chemistry, biology, and materials science play out. These facilities have played a pivotal role in numerous scientific breakthroughs, such as producing the first “molecular movie” that reveals the intricacies of complex chemical reactions, capturing the precise moments when plants and algae harness solar energy to generate the oxygen we rely on, and probing the intense conditions that shape the formation of planets and extraordinary events like diamond precipitation.

Over the years, SLAC has evolved to support a growing community of scientists. As of 2021, the lab employs approximately 1,600 staff members from 55 different countries, in addition to 470 postdoctoral researchers and graduate students. The center welcomes over 3,000 visiting researchers annually​​. This community has access to facilities such as the Stanford Synchrotron Radiation Lightsource for materials science and biology experiments and the Fermi Gamma-ray Space Telescope for astrophysics research​​.

After decades of effort and help from SLAC’s X-ray laser, scientists have finally seen the process by which nature creates the oxygen we breathe. (SLAC)

The lab is also working at the forefront of astronomy and imaging. The SLAC National Accelerator Laboratory is at the helm of an ambitious project, crafting the world’s largest digital camera for the Vera Rubin Observatory’s Legacy Survey of Space and Time (LSST). Set to capture the southern sky from high on a mountaintop in Chile, this camera is a marvel of engineering and scientific collaboration. Its 3.2-gigapixel capacity allows it to snap detailed images every 15 seconds, offering an unprecedented window into the cosmos. The camera’s wide field of view can image an area 40 times larger than the full moon in one shot, and its advanced filters enable astronomers to probe the universe across a range of wavelengths. As part of the decade-long LSST, it will gather vast amounts of data, propelling our understanding of dark matter, dark energy, galaxy formation, and more​

SLAC has developed the world’s largest digital camera for the Vera Rubin Observatory’s Legacy Survey of Space and Time (LSST)

In 2008, the lab was renamed from the Stanford Linear Accelerator Center to SLAC National Accelerator Laboratory, reflecting a broader scientific mission. Since then, the lab has continued to receive significant funding, including $68.3 million in Recovery Act Funding in 2009​​. Notably, SLAC and Stanford University initiated the Bits and Watts project to develop better, greener electric grids, although SLAC later withdrew due to concerns over an industry partner​​.

SLAC’s current endeavors include the Facility for Advanced Accelerator Experimental Tests (FACET), where research on plasma acceleration continues to advance the field​​. Theoretical research at the lab spans quantum field theory, collider physics, astroparticle physics, and particle phenomenology​​. Moreover, SLAC has contributed to the development of the klystron, a high-power microwave amplification tube that amplifies high radio frequencies and has aided in archaeological discoveries such as revealing hidden text in the Archimedes Palimpsest​​.

Archimedes Palimpsest (Wikipedia)

Other recent updates from SLAC include a new system for turning seawater into hydrogen fuel​​​​. They have also made advancements in understanding the production of nitroxide, a molecule with potential biomedical applications, and the operation of superconducting X-ray lasers at temperatures colder than outer space​​​​.

The SLAC National Accelerator Laboratory’s legacy is rich with scientific triumphs, and its future beckons with the promise of unraveling more of the universe’s deepest secrets. Whether through peering into the atomic structure or probing the vast cosmos, SLAC remains a beacon of discovery and innovation.

J. Robert Oppenheimer: The Berkeley Era and The Birth of the Manhattan Project

With the release of the movie Oppenheimer, it’s worth taking a look at the role that California played in one of the most important technological developments of the 20th century: the making of the atomic bomb. The Manhattan Project, the prodigious scientific endeavor that produced the world’s first nuclear weapons, cast a long, dark shadow over the mid-20th century. But amid the mushroom clouds, there lies a tale of innovation and scientific genius that originated from an unlikely source—the University of California, Berkeley.

The film team filmed several scenes at Berkeley, adding a vintage car and 1940s-era lampposts to the campus. Oppenheimer taught at UC Berkeley from 1929 to 1943 — his office was on the third floor of Physics North (then named LeConte Hall) 

For years, America’s physics powerhouse resided in the East. But in the post-WWI era, the western horizon blazed with opportunity. Visionary administrators at Caltech and UC Berkeley threw financial muscle behind their bold mission: to make physics research a priority.

By the dawn of the 1930s, their investments bore fruit. The American Physical Society‘s president hailed California as a hotbed of physics innovation, equating it with the East in the academic landscape of the discipline. Universities played high-stakes poker for the talents of up-and-coming physicists like Oppenheimer and Ernest Lawrence, known for his groundbreaking work in photoelectricity and ionization.

J. Robert Oppenheimer, one of the leading physicists of the 20th century, is often remembered as the ‘father of the atomic bomb’. However, his journey toward this formidable title began at the University of California, Berkeley, an intellectual crucible where his talent for theoretical physics was honed, ultimately leading him to oversee the Manhattan Project, a scientific endeavor that would change the world.

Oppenheimer’s relationship with Berkeley began in 1929 when he joined as an Assistant Professor of Physics. This was an exciting period in the realm of science. Quantum mechanics was in its infancy and a new breed of scientists was emerging, eager to unlock the secrets of the universe. Oppenheimer, with his insatiable curiosity and infectious enthusiasm, was just the right person for this time of exploration.

During his years at Berkeley, Oppenheimer made significant contributions to quantum mechanics, notably his work on the Oppenheimer-Phillips process. This theory describes a particular type of nuclear reaction that occurs during the absorption of a neutron by a nucleus, an understanding that would later prove pivotal to the development of nuclear energy.

Outside the laboratory, Oppenheimer was an adored figure, known for his quick wit and charismatic teaching style. He was instrumental in building the physics program at Berkeley into perhaps the finest in the country by attracting some of the brightest minds of the time. Together, they would be known as dubbed the “luminaries”.

Ed Westcott/U.S. Department of Energy via Bay City News

“The group met secretly in his office at the northwest corner of the top floor of ‘old’ LeConte Hall. This office, like others on the top floor, has glass doors opening out onto a balcony. This balcony is readily accessible from the roof. To prevent this method of entry, a very heavy iron netting was placed over the balcony. A special lock was placed on the door to the office and only Oppenheimer had the key. No janitor could enter the office, nor could I, as chairman of the department,” Raymond T. Birge, former chair of the Berkeley physics department at the time, said in his “History of the Physics Department.”

Hans Bethe, one of the great German-American theoretical physicists of the age said Oppenheimer established UC Berkeley as the “greatest school of theoretical physics the United States has ever known.”

Although he was increasingly recognized as a pivotal figure in theoretical physics, former students say he remained accessible, consistently urging his students to question norms and extend limits. He actively promoted a culture of inquiry among his students, even if his responses occasionally seemed harsh. However, Oppenheimer’s questions to his student speakers were meant to clarify rather than to humiliate, often aimed more at enlightening the audience than himself. His rapport with his students was unexpectedly casual. He provided an open-door policy, inviting his students to visit his office anytime to utilize the physics resources within his personal collection.

Oppenheimer’s life at Berkeley wasn’t all physics. A man of varied interests, he was an avid hiker, horseback rider, and aficionado of literature, poetry, and art. These varied interests made him a multifaceted character and helped him foster connections with many prominent figures across different fields. His unique combination of scientific genius, humanity, and leadership qualities made him a standout candidate for the enormous task that lay ahead – the Manhattan Project.

While no major Manhattan Project facilities graced the Golden State, Berkeley, nestled in the heart of California, emerged as an unsung hero of the project, becoming a breeding ground for some of the brightest American scientific minds. Berkeley offered more than a tranquil academic setting; it provided an assembly line of experts that would revolutionize nuclear science. Not only was Berkeley home to Oppenheimer the university also attracted other nuclear-era luminaries like Ernest Lawrence, and chemists Glenn Seaborg.

Berkeley had always been special. California’s first land-grant university, founded in 1868, Berkeley underwent a metamorphosis under the leadership of Robert Sproul. From 1930 to 1958, Sproul spearheaded the transformation of Berkeley into a hub of intellectual firepower. The University of California system burgeoned across the state, with Berkeley, the original campus, earning a reputation as one of the nation’s foremost research institutions. Its powerhouse physics department became a beacon in the dark world of the Manhattan Project.

Berkeley’s list of accomplishments is long and distinguished, but one discovery stands out – the identification of plutonium. Edwin McMillan, a promising physicist at Berkeley, ventured into the wilderness of uranium fission products. In 1940, he stumbled upon an unknown substance – element 93, or as he named it, “neptunium,” a hat tip to the distant planet Neptune. McMillan predicted that neptunium decayed into plutonium, the elusive element 94.

Glenn Seabord – Wikipedia

Glenn Seaborg, another Berkeley savant, picked up where McMillan left off when the latter migrated east to work at MIT. Seaborg unveiled the heart of plutonium, exposing its fundamental chemical and nuclear properties, including its high propensity for fission. As the world’s leading expert on plutonium, Seaborg directed the ambitious effort to separate plutonium from uranium and other reactor products.

Ernest Lawrence, a key player in the Berkeley camp, led a research group that broke boundaries with the cyclotrons at the Rad Lab. They used the 60-inch cyclotron to bombard uranium with neutrons, producing plutonium for scrutiny. But Lawrence had a brainwave. In 1941, he realized the cyclotron could also operate as a mass spectrometer, effectively isolating uranium-235 from uranium-238. This technique was later adopted at Oak Ridge’s Y-12 Separation Plant, enabling large-scale separation. The cyclotron, rechristened as a “Calutron” in a nod to the University of California, had revolutionized nuclear science.

J. Robert Oppenheimer (Midjourney)

While these figures were all played prominent roles in the development of the atomic bomb dropped on Hiroshima and Nagasaki in 1945, it is Oppenheimer who is best remembered. After fourteen years at Berkeley, Oppenheimer was plucked from the physics department at Berkley to assume leadership of the research program at Los Alamos. Even after his move, Oppenheimer fostered a close alliance between Berkeley and the Manhattan Project. In a shroud of secrecy, the University of California took on the management of the operations at Los Alamos. The university even set up a Los Angeles office that handled material logistics for the lab.

Despite decades passing and the veils of secrecy lifting, the legacy endures. The Los Alamos lab continues to operate under the University of California’s management, preserving Berkeley’s indelible imprint on the atomic age. It’s a testament to the institution’s groundbreaking contributions and a tribute to the remarkable scientists who once walked its hallowed halls.